Cryo-EM and directed evolution reveal how Arabidopsis nitrilase specificity is influenced by its qua...
Cryo-EM and directed evolution reveal how Arabidopsis nitrilase specificity is influenced by its quaternary structure
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Nitrilases are helical enzymes that convert nitriles to acids and/or amides. All plants have a nitrilase 4 homolog specific for ß-cyanoalanine, while in some plants neofunctionalization has produced nitrilases with altered specificity. Plant nitrilase substrate size and specificity correlate with helical twist, but molecular details of this relatio...
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Cryo-EM and directed evolution reveal how Arabidopsis nitrilase specificity is influenced by its quaternary structure
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6637149
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6637149
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2399-3642
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2399-3642
DOI
10.1038/s42003-019-0505-4
