Paf1C regulates RNA polymerase II progression by modulating elongation rate
Paf1C regulates RNA polymerase II progression by modulating elongation rate
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Elongation factor Paf1C regulates several stages of the RNA polymerase II (Pol II) transcription cycle, although it is unclear how it modulates Pol II distribution and progression in mammalian cells. We found that conditional ablation of Paf1 resulted in the accumulation of unphosphorylated and Ser5 phosphorylated Pol II around promoter-proximal re...
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Full title
Paf1C regulates RNA polymerase II progression by modulating elongation rate
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6642404
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6642404
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1904324116
