Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory...
Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Memory T cells are critical for the immune response to recurring infections. Their instantaneous reactivity to pathogens is empowered by the persistent expression of cytokine-encoding mRNAs. How the translation of proteins from pre-formed cytokine-encoding mRNAs is prevented in the absence of infection has remained unclear. Here we found that prote...
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Full title
Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6643272
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6643272
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0155-6
