An oligo-His-tag of a targeting module does not influence its biodistribution and the retargeting ca...
An oligo-His-tag of a targeting module does not influence its biodistribution and the retargeting capabilities of UniCAR T cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Recently, we established the controllable modular UniCAR platform technology to advance the efficacy and safety of CAR T cell therapy. The UniCAR system is composed of (i) target modules (TMs) and (ii) UniCAR armed T cells. TMs are bispecific molecules that are able to bind to the tumor cell surface and simultaneously to UniCAR T cells. For interac...
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An oligo-His-tag of a targeting module does not influence its biodistribution and the retargeting capabilities of UniCAR T cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6646371
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6646371
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-47044-4