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NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-...

NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6647258

NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-related genes expression

About this item

Full title

NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-related genes expression

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2019-08, Vol.76 (15), p.3005-3018

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The accumulation of intracellular β-amyloid peptide (Aβ) is important pathological characteristic of Alzheimer’s disease (AD). However, the exact underlying molecular mechanism remains to be elucidated. Here, we reported that Nuclear Paraspeckle Assembly Transcript 1 (NEAT1), a long n on-coding RNA, exhibits repressed expression in the early stage...

Alternative Titles

Full title

NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-related genes expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6647258

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6647258

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-019-03074-9

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