Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis
Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The Muc-1 oncoprotein is a tumor-associated mucin often overexpressed in pancreatic cancer. We report that knockout of Muc-1 reduced the degree of pancreatic inflammation that resulted from infection with Coxsackievirus B3 (CVB3) in a mouse model. CVB3-infected Muc-1-deficient (Muc-1
KO
) mice had significantly reduced infiltration of macroph...
Alternative Titles
Full title
Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650496
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650496
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-46933-y
