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WDFY4 is required for cross-presentation in response to viral and tumor antigens

WDFY4 is required for cross-presentation in response to viral and tumor antigens

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6655551

WDFY4 is required for cross-presentation in response to viral and tumor antigens

About this item

Full title

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6415), p.694-699

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Immune responses to viral or tumor antigens are typically initiated by the process of cross-presentation. Cross-presentation is believed to be the major way that innate immune cells, such as the classical dendritic cell 1 (cDC1) subset, activate and prime immunological T cells. Theisen
et al.
used CRISPR-based screening to identify regulators...

Alternative Titles

Full title

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6655551

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6655551

Other Identifiers

ISSN

0036-8075,1095-9203

E-ISSN

1095-9203

DOI

10.1126/science.aat5030

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