Global view of the RAF-MEK-ERK module and its immediate downstream effectors
Global view of the RAF-MEK-ERK module and its immediate downstream effectors
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Small molecule inhibitors of BRAF and MEK have proven effective at inhibiting tumor growth in melanoma patients, however this efficacy is limited due to the almost universal development of drug resistance. To provide advanced insight into the signaling responses that occur following kinase inhibition we have performed quantitative (phospho)-proteom...
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Full title
Global view of the RAF-MEK-ERK module and its immediate downstream effectors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659682
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659682
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-47245-x
