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Activity-dependent changes in synaptic protein complex composition are consistent in different deter...

Activity-dependent changes in synaptic protein complex composition are consistent in different deter...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659712

Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility

About this item

Full title

Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-07, Vol.9 (1), p.10890-15, Article 10890

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

At the post-synaptic density (PSD), large protein complexes dynamically form and dissociate in response to synaptic activity, comprising the biophysical basis for learning and memory. The use of detergents to isolate the PSD and release its membrane-associated proteins complicates studies of these activity-dependent protein interaction networks, be...

Alternative Titles

Full title

Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659712

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659712

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-46690-y

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