Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast can...
Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer
About this item
Full title
Author / Creator
Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Scope and Contents
Contents
Purpose
The serine-threonine kinases Aurora A (AURKA) and p21-activated kinase 1 (PAK1) are frequently overexpressed in breast tumors, with overexpression promoting aggressive breast cancer phenotypes and poor clinical outcomes. Besides the well-defined roles of these proteins in control of cell division, proliferation, and invasion, both kinase...
Alternative Titles
Full title
Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6661032
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6661032
Other Identifiers
ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-019-05329-2
