Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome
Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome
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Author / Creator
Balistreri, Carmela R. , Marullo, Antonino G. M. , Madonna, Michele , Cavarretta, Elena , Allegra, Alberto , Cesarini, Valeriana , Iaccarino, Alessandra , Schiavon, Sonia , Peruzzi, Mariangela , Greco, Ernesto , Sciarretta, Sebastiano , Pisano, Calogera , Ruvolo, Giovanni , Torella, Michele and Frati, Giacomo
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Bicuspid aortic valve (BAV) disease is recognized to be a
syndrome
with a complex and multifaceted pathophysiology. Its progression is modulated by diverse evolutionary conserved pathways, such as Notch-1 pathway. Emerging evidence is also highlighting the key role of TLR4 signaling pathway in the aortic valve pathologies and their related co...
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Full title
Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6667442
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6667442
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-47412-0