Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis
Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis
About this item
Full title
Author / Creator
Masterson, Joanne C. , Biette, Kathryn A. , Hammer, Juliet A. , Nguyen, Nathalie , Capocelli, Kelley E. , Saeedi, Bejan J. , Harris, Rachel F. , Fernando, Shahan D. , Hosford, Lindsay B. , Kelly, Caleb J. , Campbell, Eric L. , Ehrentraut, Stefan F. , Ahmed, Faria N. , Nakagawa, Hiroshi , Lee, James J. , McNamee, Eóin N. , Glover, Louise E. , Colgan, Sean P. and Furuta, Glenn T.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Epithelial barrier dysfunction is a significant factor in many allergic diseases, including eosinophilic esophagitis (EoE). Infiltrating leukocytes and tissue adaptations increase metabolic demands and decrease oxygen availability at barrier surfaces. Understanding of how these processes impact barrier is limited, particularly in allergy. Here, we...
Alternative Titles
Full title
Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis
Authors, Artists and Contributors
Author / Creator
Biette, Kathryn A.
Hammer, Juliet A.
Nguyen, Nathalie
Capocelli, Kelley E.
Saeedi, Bejan J.
Harris, Rachel F.
Fernando, Shahan D.
Hosford, Lindsay B.
Kelly, Caleb J.
Campbell, Eric L.
Ehrentraut, Stefan F.
Ahmed, Faria N.
Nakagawa, Hiroshi
Lee, James J.
McNamee, Eóin N.
Glover, Louise E.
Colgan, Sean P.
Furuta, Glenn T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668670
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668670
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI126744