Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature
Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Oxidative stress plays an important role in aging-related neurodegeneration. This study used littermates of WT and Nox2-knockout (Nox2KO) mice plus endothelial cell-specific human Nox2 overexpression-transgenic (HuNox2Tg) mice to investigate Nox2-derived ROS in brain aging. Compared with young WT mice (3-4 months), aging WT mice (20-22 months) had...
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Full title
Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668817
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668817
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI125173
