Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair
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Author / Creator
Shook, Brett A , Wasko, Renee R , Rivera-Gonzalez, Guillermo C , Salazar-Gatzimas, Emilio , López-Giráldez, Francesc , Dash, Biraja C , Muñoz-Rojas, Andrés R , Aultman, Krystal D , Zwick, Rachel K , Lei, Vivian , Arbiser, Jack L , Miller-Jensen, Kathryn , Clark, Damon A , Hsia, Henry C and Horsley, Valerie
Publisher
United States: The American Association for the Advancement of Science
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Language
English
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Publisher
United States: The American Association for the Advancement of Science
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Scope and Contents
Contents
During tissue repair, myofibroblasts produce extracellular matrix (ECM) molecules for tissue resilience and strength. Altered ECM deposition can lead to tissue dysfunction and disease. Identification of distinct myofibroblast subsets is necessary to develop treatments for these disorders. We analyzed profibrotic cells during mouse skin wound healin...
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Full title
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6684198
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6684198
Other Identifiers
ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.aar2971