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Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6685948

Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

About this item

Full title

Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-08, Vol.9 (1), p.11460-8, Article 11460

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms include deletion or insertion mutations in ribosomal protein uL22, which lead to alterations of the...

Alternative Titles

Full title

Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6685948

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6685948

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-48019-1

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