Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant
Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms include deletion or insertion mutations in ribosomal protein uL22, which lead to alterations of the...
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Full title
Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6685948
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6685948
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-48019-1