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Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition

Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6689241

Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition

About this item

Full title

Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition

Publisher

London: Nature Publishing Group UK

Journal title

Nature microbiology, 2019-05, Vol.4 (5), p.800-812

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Host NOD-like receptor family pyrin domain-containing 6 (NLRP6) regulates innate immune responses and gastrointestinal homeostasis. Its protective role in intestinal colitis and tumorigenesis is dependent on the host microbiome. Host innate immunity and microbial diversity also play a role in the severity of allogeneic immune-mediated gastrointesti...

Alternative Titles

Full title

Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6689241

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6689241

Other Identifiers

ISSN

2058-5276

E-ISSN

2058-5276

DOI

10.1038/s41564-019-0373-1

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