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Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6690032

Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

About this item

Full title

Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (32), p.15774-15783

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

CRISPR-Cas systems are now widely used for genome editing and transcriptional regulation in diverse organisms. The compact and portable nature of class 2 single effector nucleases, such as Cas9 or Cas12, has facilitated directed genome modifications in plants, animals, and microbes. However, most CRISPR-Cas systems belong to the more prevalent clas...

Alternative Titles

Full title

Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6690032

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6690032

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1905421116

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