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Non-canonical functions of the RB protein in cancer

Non-canonical functions of the RB protein in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6693677

Non-canonical functions of the RB protein in cancer

About this item

Full title

Non-canonical functions of the RB protein in cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2018-07, Vol.18 (7), p.442-451

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The canonical model of RB-mediated tumour suppression developed over the past 30 years is based on the regulation of E2F transcription factors to restrict cell cycle progression. Several additional functions have been proposed for RB, on the basis of which a non-canonical RB pathway can be described. Mechanistically, the non-canonical RB pathway pr...

Alternative Titles

Full title

Non-canonical functions of the RB protein in cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6693677

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6693677

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/s41568-018-0008-5

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