Non-canonical functions of the RB protein in cancer
Non-canonical functions of the RB protein in cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The canonical model of RB-mediated tumour suppression developed over the past 30 years is based on the regulation of E2F transcription factors to restrict cell cycle progression. Several additional functions have been proposed for RB, on the basis of which a non-canonical RB pathway can be described. Mechanistically, the non-canonical RB pathway pr...
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Full title
Non-canonical functions of the RB protein in cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6693677
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6693677
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/s41568-018-0008-5