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Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving...

Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6702672

Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis

About this item

Full title

Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Diabetologia, 2019-05, Vol.62 (5), p.860-872

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aims/hypothesis
The role of non-cardiomyocytes in diabetic cardiomyopathy has not been fully addressed. This study investigated whether endothelial cell calpain plays a role in myocardial endothelial injury and microvascular rarefaction in diabetes, thereby contributing to diabetic cardiomyopathy.
Methods
Endothelial cell-specific
Capns...

Alternative Titles

Full title

Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6702672

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6702672

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-019-4828-y

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