Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms
Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Aneurysms and dissections affecting thoracic aorta are associated with smooth muscle cell (SMC) dysfunction. NO/cGMP signaling pathway in smooth muscle cells has been shown to be affected in sporadic thoracic aortic aneurysms. We analyzed the mRNA levels of PDE5, a cGMP-hydrolyzing enzyme highly expressed in aortic SMCs, that regulates arterious va...
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Full title
Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6704119
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6704119
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-48432-6
