β Cell–intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion
β Cell–intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Beta-arrestin-1 and -2 (Barr1 and Barr2, respectively) are intracellular signaling molecules that regulate many important metabolic functions. We previously demonstrated that mice lacking Barr2 selectively in pancreatic beta-cells showed pronounced metabolic impairments. Here we investigated whether Barr1 plays a similar role in regulating beta-cel...
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Full title
β Cell–intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6715363
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6715363
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI126309
