Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome...
Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms
About this item
Full title
Author / Creator
Botschuijver, Sara , van Diest, Sophie A. , van Thiel, Isabelle A. M. , Saia, Rafael S. , Strik, Anne S. , Yu, Zhumei , Maria-Ferreira, Daniele , Welting, Olaf , Keszthelyi, Daniel , Jennings, Gary , Heinsbroek, Sigrid E. M. , Elferink, Ronald P. Oude , Schuren, Frank H. J. , de Jonge, Wouter J. and van den Wijngaard, René M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Irritable bowel syndrome (IBS) is a heterogenic, functional gastrointestinal disorder of the gut-brain axis characterized by altered bowel habit and abdominal pain. Preclinical and clinical results suggested that, in part of these patients, pain may result from fungal induced release of mast cell derived histamine, subsequent activation of sensory...
Alternative Titles
Full title
Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6715706
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6715706
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-49096-y
