ELISA units, IgG subclass ratio and avidity determined functional activity of mouse anti-Pfs230 anti...
ELISA units, IgG subclass ratio and avidity determined functional activity of mouse anti-Pfs230 antibodies judged by a standard membrane-feeding assay with Plasmodium falciparum
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Contents
•Multiple mouse anti-Pfs230 antibodies were generated for ELISA and SMFA tests.•There was a significant correlation between ELISA titer and SMFA activity.•However, ELISA titer alone was a poor predictor of functional activity.•Both IgG2/IgG1 ratio and avidity significantly affected functional activity.
The standard membrane-feeding assay (SMFA)...
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Full title
ELISA units, IgG subclass ratio and avidity determined functional activity of mouse anti-Pfs230 antibodies judged by a standard membrane-feeding assay with Plasmodium falciparum
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6718089
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6718089
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2019.02.071
