The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: Effi...
The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: Efficacy and Safety Observations
About this item
Full title
Author / Creator
Ferreira, Tiago , Campos, Sandra , Silva, Mónica G. , Ribeiro, Rita , Santos, Susana , Almeida, José , Pires, Maria João , Gil da Costa, Rui Miguel , Córdova, Cláudia , Nogueira, António , Neuparth, Maria João , Medeiros, Rui , Monteiro Bastos, Margarida Maria da Silva , Gaivão, Isabel , Peixoto, Francisco , Oliveira, Maria Manuel and Oliveira, Paula Alexandra
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
Carcinogenesis induced by high-risk human papillomavirus (HPV) involves inflammatory phenomena, partially mediated by cyclooxigenase-2. In pre-clinical models of HPV-induced cancer, cyclooxygenase-2 inhibitors have shown significant efficacy, but also considerable toxicity. This study addresses the chemopreventive effect and hepatic toxicity of a s...
Alternative Titles
Full title
The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: Efficacy and Safety Observations
Authors, Artists and Contributors
Author / Creator
Campos, Sandra
Silva, Mónica G.
Ribeiro, Rita
Santos, Susana
Almeida, José
Pires, Maria João
Gil da Costa, Rui Miguel
Córdova, Cláudia
Nogueira, António
Neuparth, Maria João
Medeiros, Rui
Monteiro Bastos, Margarida Maria da Silva
Gaivão, Isabel
Peixoto, Francisco
Oliveira, Maria Manuel
Oliveira, Paula Alexandra
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6720853
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6720853
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms20163902
