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Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in huma...

Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in huma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6722002

Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells

About this item

Full title

Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2019-09, Vol.51 (9), p.1380-1388

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Chromatin architecture has been implicated in cell type-specific gene regulatory programs, yet how chromatin remodels during development remains to be fully elucidated. Here, by interrogating chromatin reorganization during human pluripotent stem cell (hPSC) differentiation, we discover a role for the primate-specific endogenous retrotransposon hum...

Alternative Titles

Full title

Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6722002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6722002

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-019-0479-7

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