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Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoi...

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6724216

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

About this item

Full title

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Publisher

England: Elsevier Limited

Journal title

Annals of the rheumatic diseases, 2017-11, Vol.76 (11), p.1915-1923

Language

English

Formats

Publication information

Publisher

England: Elsevier Limited

More information

Scope and Contents

Contents

ObjectiveThe pathogenetic mechanisms by which HLA-DRB1 alleles are associated with anticitrullinated peptide antibody (ACPA)-positive rheumatoid arthritis (RA) are incompletely understood. RA high-risk HLA-DRB1 alleles are known to share a common motif, the ‘shared susceptibility epitope (SE)’. Here, the electropositive P4 pocket of HLA-DRB1 accomm...

Alternative Titles

Full title

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6724216

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6724216

Other Identifiers

ISSN

0003-4967

E-ISSN

1468-2060

DOI

10.1136/annrheumdis-2017-211300

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