Excitotoxic neurodegeneration is associated with a focal decrease in metabotropic glutamate receptor...
Excitotoxic neurodegeneration is associated with a focal decrease in metabotropic glutamate receptor type 5 availability: an in vivo PET imaging study
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Metabotropic glutamate receptors (mGluRs) have been proposed as promising therapeutic targets to correct the dysregulated glutamate signaling, associated with neurodegenerative pathologies. Of all mGluR subtypes, especially mGluR5 acts as a modulator of glutamate-induced excitotoxicity. To study the behavior of mGluR5 following localized excitotoxi...
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Excitotoxic neurodegeneration is associated with a focal decrease in metabotropic glutamate receptor type 5 availability: an in vivo PET imaging study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6733799
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6733799
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-49356-x