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Galectin 3 protects from cisplatin-induced acute kidney injury by promoting TLR-2-dependent activati...

Galectin 3 protects from cisplatin-induced acute kidney injury by promoting TLR-2-dependent activati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6735380

Galectin 3 protects from cisplatin-induced acute kidney injury by promoting TLR-2-dependent activation of IDO1/Kynurenine pathway in renal DCs

About this item

Full title

Galectin 3 protects from cisplatin-induced acute kidney injury by promoting TLR-2-dependent activation of IDO1/Kynurenine pathway in renal DCs

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

Theranostics, 2019-01, Vol.9 (20), p.5976-6001

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

Strategies targeting cross-talk between immunosuppressive renal dendritic cells (DCs) and T regulatory cells (Tregs) may be effective in treating cisplatin (CDDP)-induced acute kidney injury (AKI). Galectin 3 (Gal-3), expressed on renal DCs, is known as a crucial regulator of immune response in the kidneys. In this study, we investigated the role o...

Alternative Titles

Full title

Galectin 3 protects from cisplatin-induced acute kidney injury by promoting TLR-2-dependent activation of IDO1/Kynurenine pathway in renal DCs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6735380

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6735380

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.33959

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