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RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6736635

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

About this item

Full title

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2019-03, Vol.26 (3), p.237-247

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Polycomb repressive complex 2 (PRC2) is a histone methyltransferase that maintains cell identity during development in multicellular organisms by marking repressed genes and chromatin domains. In addition to four core subunits, PRC2 comprises multiple accessory subunits that vary in their composition during cellular differentiation and define two m...

Alternative Titles

Full title

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6736635

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6736635

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/s41594-019-0197-y

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