Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to...
Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Background
Recurrence after >5-year disease-free survival affects one-fifth of breast cancer patients and is the clinical manifestation of cancer cell reactivation after persistent dormancy.
Methods
We investigated cellular dormancy in vitro and in vivo using breast cancer cell lines and cell and molecular biology techniques.
Results
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Full title
Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6738045
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6738045
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ISSN
0007-0920,1532-1827
E-ISSN
1532-1827
DOI
10.1038/s41416-019-0501-y