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Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to...

Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6738045

Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry

About this item

Full title

Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2019-07, Vol.121 (2), p.157-171

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
Recurrence after >5-year disease-free survival affects one-fifth of breast cancer patients and is the clinical manifestation of cancer cell reactivation after persistent dormancy.
Methods
We investigated cellular dormancy in vitro and in vivo using breast cancer cell lines and cell and molecular biology techniques.
Results

Alternative Titles

Full title

Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6738045

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6738045

Other Identifiers

ISSN

0007-0920,1532-1827

E-ISSN

1532-1827

DOI

10.1038/s41416-019-0501-y

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