ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells...
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins
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Author / Creator
Al-Ismaeel, Qais , Neal, Christopher P. , Al-Mahmoodi, Hanaa , Almutairi, Zamzam , Al-Shamarti, Ibtihal , Straatman, Kees , Jaunbocus, Nabil , Irvine, Andrew , Issa, Eyad , Moreman, Catherine , Dennison, Ashley R. , Emre Sayan, A. , McDearmid, Jonathan , Greaves, Peter , Tulchinsky, Eugene and Kriajevska, Marina
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Background
S100 proteins have been implicated in various aspects of cancer, including epithelial-mesenchymal transitions (EMT), invasion and metastasis, and also in inflammatory disorders. Here we examined the impact of individual members of this family on the invasion of pancreatic ductal adenocarcinoma (PDAC) cells, and their regulation by EMT...
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Full title
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6738112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6738112
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-019-0483-9