Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed...
Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells
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Author / Creator
El Maadidi, Souhayla , Weber, Alexander N. R. , Motshwene, Precious , Schüssler, Jan Moritz , Backes, Daniel , Dickhöfer, Sabine , Wang, Hui , Liu, Xiao , Garcia, Magno Delmiro , Taumer, Christoph , Soufi, Boumediene , Wolz, Olaf-Oliver , Klimosch, Sascha N. , Franz-Wachtel, Mirita , Macek, Boris and Gay, Nicholas J.
Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Toll-like receptors (TLRs) are important sentinels of bacterial and viral infection and thus fulfil a critical sensory role in innate immunity. Polo-like kinases (PLKs), a five membered family of Ser/Thr protein kinases, have long been studied for their role in mitosis and thus represent attractive therapeutic targets in cancer therapy. Recently, P...
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Full title
Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6739412
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6739412
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-49017-z
