Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficie...
Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficiency
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Gene therapy for X-linked severe combined immunodeficiency (SCID-X1) has proven highly effective for long-term restoration of immunity in human subjects. However, the development of lymphoproliferative complications due to dysregulated proto-oncogene expression has underlined the necessity for developing safer vector systems. To reduce the potentia...
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Full title
Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficiency
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6748866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6748866
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/sj.mt.6300393