Refinements of LC-MS/MS Spectral Counting Statistics Improve Quantification of Low Abundance Protein...
Refinements of LC-MS/MS Spectral Counting Statistics Improve Quantification of Low Abundance Proteins
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Mass spectrometry-based spectral count has been a common choice of label-free proteome quantification due to the simplicity for the sample preparation and data generation. The discriminatory nature of spectral count in the MS data-dependent acquisition, however, inherently introduces the spectral count variation for low-abundance proteins in multip...
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Full title
Refinements of LC-MS/MS Spectral Counting Statistics Improve Quantification of Low Abundance Proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6754416
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6754416
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-49665-1
