NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive...
NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We previously showed that NADPH oxidase organizer 1 (Noxo1), a component of NADPH oxidase 1 (NOX1), is a TNF-α-induced tumor-promoting factor in gastric tumorigenesis. However, the mechanism of NOX1-induced reactive oxygen species (ROS) signaling for the gastric tumorigenesis has not been understood. Here, we showed that expression of NOX1 complex...
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NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6756228
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6756228
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-0702-0
