Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress
Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress
About this item
Full title
Author / Creator
Conde, Cecilia Domínguez , Petronczki, Özlem Yüce , Baris, Safa , Willmann, Katharina L , Girardi, Enrico , Salzer, Elisabeth , Weitzer, Stefan , Ardy, Rico Chandra , Krolo, Ana , Ijspeert, Hanna , Kiykim, Ayca , Karakoc-Aydiner, Elif , Förster-Waldl, Elisabeth , Kager, Leo , Pickl, Winfried F , Superti-Furga, Giulio , Martínez, Javier , Loizou, Joanna I , Ozen, Ahmet , van der Burg, Mirjam and Boztug, Kaan
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Polymerase δ is essential for eukaryotic genome duplication and synthesizes DNA at both the leading and lagging strands. The polymerase δ complex is a heterotetramer comprising the catalytic subunit POLD1 and the accessory subunits POLD2, POLD3, and POLD4. Beyond DNA replication, the polymerase δ complex has emerged as a central element in genome m...
Alternative Titles
Full title
Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress
Authors, Artists and Contributors
Author / Creator
Petronczki, Özlem Yüce
Baris, Safa
Willmann, Katharina L
Girardi, Enrico
Salzer, Elisabeth
Weitzer, Stefan
Ardy, Rico Chandra
Krolo, Ana
Ijspeert, Hanna
Kiykim, Ayca
Karakoc-Aydiner, Elif
Förster-Waldl, Elisabeth
Kager, Leo
Pickl, Winfried F
Superti-Furga, Giulio
Martínez, Javier
Loizou, Joanna I
Ozen, Ahmet
van der Burg, Mirjam
Boztug, Kaan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6763221
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6763221
Other Identifiers
ISSN
0021-9738,1558-8238
E-ISSN
1558-8238
DOI
10.1172/JCI128903
