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Landscape of B cell immunity and related immune evasion in human cancers

Landscape of B cell immunity and related immune evasion in human cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6773274

Landscape of B cell immunity and related immune evasion in human cancers

About this item

Full title

Landscape of B cell immunity and related immune evasion in human cancers

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2019-03, Vol.51 (3), p.560-567

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Tumor-infiltrating B cells are an important component in the microenvironment but have unclear anti-tumor effects. We enhanced our previous computational algorithm TRUST to extract the B cell immunoglobulin hypervariable regions from bulk tumor RNA-sequencing data. TRUST assembled more than 30 million complementarity-determining region 3 sequences...

Alternative Titles

Full title

Landscape of B cell immunity and related immune evasion in human cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6773274

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6773274

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-018-0339-x

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