Genome-wide cell-free DNA fragmentation in patients with cancer
Genome-wide cell-free DNA fragmentation in patients with cancer
About this item
Full title
Author / Creator
Cristiano, Stephen , Leal, Alessandro , Phallen, Jillian , Fiksel, Jacob , Adleff, Vilmos , Bruhm, Daniel C. , Jensen, Sarah Østrup , Medina, Jamie E. , Hruban, Carolyn , White, James R. , Palsgrove, Doreen N. , Niknafs, Noushin , Anagnostou, Valsamo , Forde, Patrick , Naidoo, Jarushka , Marrone, Kristen , Brahmer, Julie , Woodward, Brian D. , Husain, Hatim , van Rooijen, Karlijn L. , Ørntoft, Mai-Britt Worm , Madsen, Anders Husted , van de Velde, Cornelis J. H. , Verheij, Marcel , Cats, Annemieke , Punt, Cornelis J. A. , Vink, Geraldine R. , van Grieken, Nicole C. T. , Koopman, Miriam , Fijneman, Remond J. A. , Johansen, Julia S. , Nielsen, Hans Jørgen , Meijer, Gerrit A. , Andersen, Claus Lindbjerg , Scharpf, Robert B. and Velculescu, Victor E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cell-free DNA in the blood provides a non-invasive diagnostic avenue for patients with cancer
1
. However, characteristics of the origins and molecular features of cell-free DNA are poorly understood. Here we developed an approach to evaluate fragmentation patterns of cell-free DNA across the genome, and found that profiles of healthy individ...
Alternative Titles
Full title
Genome-wide cell-free DNA fragmentation in patients with cancer
Authors, Artists and Contributors
Author / Creator
Leal, Alessandro
Phallen, Jillian
Fiksel, Jacob
Adleff, Vilmos
Bruhm, Daniel C.
Jensen, Sarah Østrup
Medina, Jamie E.
Hruban, Carolyn
White, James R.
Palsgrove, Doreen N.
Niknafs, Noushin
Anagnostou, Valsamo
Forde, Patrick
Naidoo, Jarushka
Marrone, Kristen
Brahmer, Julie
Woodward, Brian D.
Husain, Hatim
van Rooijen, Karlijn L.
Ørntoft, Mai-Britt Worm
Madsen, Anders Husted
van de Velde, Cornelis J. H.
Verheij, Marcel
Cats, Annemieke
Punt, Cornelis J. A.
Vink, Geraldine R.
van Grieken, Nicole C. T.
Koopman, Miriam
Fijneman, Remond J. A.
Johansen, Julia S.
Nielsen, Hans Jørgen
Meijer, Gerrit A.
Andersen, Claus Lindbjerg
Scharpf, Robert B.
Velculescu, Victor E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6774252
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6774252
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1272-6
