Time origin and structural analysis of the induced CRISPR/cas9 megabase-sized deletions and duplicat...
Time origin and structural analysis of the induced CRISPR/cas9 megabase-sized deletions and duplications involving the Cntn6 gene in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In a previous study using one-step CRISPR/Cas9 genome editing in mouse zygotes, we created five founders carrying a 1,137 kb deletion and two founders carrying the same deletion, plus a 2,274 kb duplication involving the
Cntn6
gene (encoding contactin-6). Using these mice, the present study had the following aims: (
i
) to establish sta...
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Time origin and structural analysis of the induced CRISPR/cas9 megabase-sized deletions and duplications involving the Cntn6 gene in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6775113
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6775113
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-50649-4
