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The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p...

The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6776551

The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53

About this item

Full title

The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2019-10, Vol.10 (10), p.750-14, Article 750

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Desmoglein-3 (Dsg3), the
Pemphigus Vulgaris (PV)
antigen (PVA), plays an essential role in keratinocyte cell–cell adhesion and regulates various signaling pathways involved in the progression and metastasis of cancer where it is upregulated. We show here that expression of Dsg3 impacts on the expression and function of p53, a key transcriptio...

Alternative Titles

Full title

The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6776551

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6776551

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-019-1988-0

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