A pathway-driven predictive model of tramadol pharmacogenetics
A pathway-driven predictive model of tramadol pharmacogenetics
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Predicting metabolizer phenotype (MP) is typically performed using data from a single gene. Cytochrome p450 family 2 subfamily D polypeptide 6 (CYP2D6) is considered the primary gene for predicting MP in reference to approximately 30% of marketed drugs and endogenous toxins. CYP2D6 predictions have proven clinically effective but also have well-doc...
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Full title
A pathway-driven predictive model of tramadol pharmacogenetics
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6777452
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6777452
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ISSN
1018-4813
E-ISSN
1476-5438
DOI
10.1038/s41431-019-0369-6
