Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
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Boston: Springer US
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Language
English
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Publisher
Boston: Springer US
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Contents
The Hedgehog (Hh) signaling pathway has been implicated in the most common childhood brain tumor, medulloblastoma (MB). Given the toxicity of post-surgical treatments for MB, continued need exists for new, targeted therapies. Based upon our finding that Neuropilin (Nrp) transmembrane proteins are required for Hh signal transduction, we investigated...
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Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6783276
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6783276
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ISSN
0167-594X
E-ISSN
1573-7373
DOI
10.1007/s11060-013-1216-1
