Multiple circulating saponins from intravenous ShenMai inhibit OATP1Bs in vitro: potential joint pre...
Multiple circulating saponins from intravenous ShenMai inhibit OATP1Bs in vitro: potential joint precipitants of drug interactions
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
ShenMai, an intravenous injection prepared from steamed
Panax ginseng
roots (Hongshen) and
Ophiopogon japonicus
roots (Maidong), is used as an add-on therapy for coronary artery disease and cancer; saponins are its bioactive constituents. Since many saponins inhibit human organic anion-transporting polypeptides (OATP)1B, this investigat...
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Full title
Multiple circulating saponins from intravenous ShenMai inhibit OATP1Bs in vitro: potential joint precipitants of drug interactions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6786436
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6786436
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/s41401-018-0173-9
