Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s dise...
Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Amyloid formation is a process involving interconverting protein species and results in toxic oligomers and fibrils. Aggregated alpha-synuclein (αS) participates in neurodegenerative maladies, but a closer understanding of the early αS polymerization stages and polymorphism of heritable αS variants is sparse still. Here, we distinguished αS oligome...
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Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789109
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789109
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-019-0598-9
