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Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastro...

Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789742

Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome

About this item

Full title

Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (41), p.20672-20678

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Radiation-induced gastrointestinal syndrome (RIGS) is a limiting factor for therapeutic abdominopelvic radiation and is predicted to be a major source of morbidity in the event of a nuclear accident or radiological terrorism. In this study, we developed an in vivo mouse-modeling platform that enables spatial and temporal manipulation of potential R...

Alternative Titles

Full title

Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789742

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789742

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1906611116

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