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Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789754

Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

About this item

Full title

Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (41), p.20517-20527

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Mitophagy is an important quality-control mechanism in eukaryotic cells, and defects in mitophagy correlate with aging phenomena and neurodegenerative disorders. It is known that different mitochondrial matrix proteins undergo mitophagy with very different rates but, to date, the mechanism underlying this selectivity at the individual protein level...

Alternative Titles

Full title

Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789754

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789754

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1901759116

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