Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation
Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Mitophagy is an important quality-control mechanism in eukaryotic cells, and defects in mitophagy correlate with aging phenomena and neurodegenerative disorders. It is known that different mitochondrial matrix proteins undergo mitophagy with very different rates but, to date, the mechanism underlying this selectivity at the individual protein level...
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Full title
Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789754
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6789754
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1901759116