Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver
Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism highly expressed in liver, metabolizes 10-formyltetrahydrofolate to produce tetrahydrofolate (THF). This reaction might have a regulatory function towards reduced folate pools,
de novo
purine biosynthesis, and the flux of folate-bound methyl groups. To understan...
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Full title
Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6797707
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6797707
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-51397-1
