2251: An estrogen receptor α (ERα)-BMPR2-apelin axis mediates 17β-estradiol’s protective effects on...
2251: An estrogen receptor α (ERα)-BMPR2-apelin axis mediates 17β-estradiol’s protective effects on right ventricular function in experimental pulmonary hypertension (PH)
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Publisher
Cambridge, UK: Cambridge University Press
Journal title
Language
English
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Publisher
Cambridge, UK: Cambridge University Press
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Scope and Contents
Contents
OBJECTIVES/SPECIFIC AIMS: Women with pulmonary arterial hypertension (PAH) exhibit superior right ventricular (RV) function and survival compared with men, a phenomenon attributed to poorly understood cardioprotective effects of 17β-estradiol (E2). We hypothesize that E2, through ERα, attenuates PH-induced RV dysfunction by upregulating the pro-con...
Alternative Titles
Full title
2251: An estrogen receptor α (ERα)-BMPR2-apelin axis mediates 17β-estradiol’s protective effects on right ventricular function in experimental pulmonary hypertension (PH)
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6804580
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6804580
Other Identifiers
ISSN
2059-8661
E-ISSN
2059-8661
DOI
10.1017/cts.2017.214
