Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
About this item
Full title
Author / Creator
Zhao, Junfei , Chen, Andrew X. , Gartrell, Robyn D. , Silverman, Andrew M. , Aparicio, Luis , Chu, Tim , Bordbar, Darius , Shan, David , Samanamud, Jorge , Mahajan, Aayushi , Filip, Ioan , Orenbuch, Rose , Goetz, Morgan , Yamaguchi, Jonathan T. , Cloney, Michael , Horbinski, Craig , Lukas, Rimas V. , Raizer, Jeffrey , Rae, Ali I. , Yuan, Jinzhou , Canoll, Peter , Bruce, Jeffrey N. , Saenger, Yvonne M. , Sims, Peter , Iwamoto, Fabio M. , Sonabend, Adam M. and Rabadan, Raul
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Immune checkpoint inhibitors have been successful across several tumor types; however, their efficacy has been uncommon and unpredictable in glioblastomas (GBM), where <10% of patients show long-term responses. To understand the molecular determinants of immunotherapeutic response in GBM, we longitudinally profiled 66 patients, including 17 long-te...
Alternative Titles
Full title
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Authors, Artists and Contributors
Author / Creator
Chen, Andrew X.
Gartrell, Robyn D.
Silverman, Andrew M.
Aparicio, Luis
Chu, Tim
Bordbar, Darius
Shan, David
Samanamud, Jorge
Mahajan, Aayushi
Filip, Ioan
Orenbuch, Rose
Goetz, Morgan
Yamaguchi, Jonathan T.
Cloney, Michael
Horbinski, Craig
Lukas, Rimas V.
Raizer, Jeffrey
Rae, Ali I.
Yuan, Jinzhou
Canoll, Peter
Bruce, Jeffrey N.
Saenger, Yvonne M.
Sims, Peter
Iwamoto, Fabio M.
Sonabend, Adam M.
Rabadan, Raul
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6810613
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6810613
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-019-0349-y
