Metabolic regulation of gene expression by histone lactylation
Metabolic regulation of gene expression by histone lactylation
About this item
Full title
Author / Creator
Zhang, Di , Tang, Zhanyun , Huang, He , Zhou, Guolin , Cui, Chang , Weng, Yejing , Liu, Wenchao , Kim, Sunjoo , Lee, Sangkyu , Perez-Neut, Mathew , Ding, Jun , Czyz, Daniel , Hu, Rong , Ye, Zhen , He, Maomao , Zheng, Y. George , Shuman, Howard A. , Dai, Lunzhi , Ren, Bing , Roeder, Robert G. , Becker, Lev and Zhao, Yingming
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The Warburg effect, which originally described increased production of lactate in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of macrophages and activation of T cells. This phenomenon is intimately linked to several diseases including neoplasia, sepsis and autoimmune diseases
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Alternative Titles
Full title
Metabolic regulation of gene expression by histone lactylation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6818755
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6818755
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1678-1
